When Fred Flarsky (Seth Rogen) reunites with his first crush, one of the most influential women in the world, Charlotte Field (Charlize Theron), he charms her with his self-deprecating humor and his memories of her youthful idealism. As she prepares to make a run for the Presidency, Charlotte hires Fred as her speechwriter. A fish out of water on Charlotte’s elite team, Fred is unprepared for her glamourous lifestyle in the limelight. Sparks fly as their unmistakable chemistry leads to a round-the-world romance and a series of unexpected and dangerous incidents.